Pharmaceutical composition containing parcetamol

Details Pharmaceutical composition containing parcetamol Pharmaceutical composition containing parcetamol

1980-01-29

1982-04-13

Friedman, Sidney J.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424280, 424324, A61U 31165, A61U 31365

Patent

active

043247784

ABSTRACT:
The acute liver toxicity effects of paracetamol are reduced by co-formulating with ascorbic acid derivatives (ascorbate anion bioprecursors) which produce high liver concentrations of ascorbate anion after oral administration of the co-formulation. A suitable ascorbate anion bioprecursor is ascorbyl 6-palmitate.

REFERENCES:
Chem. Abst., vol. 90-637 W (1979).
Rote Liste, 1967, p. 525.
Unlisted Drugs (1), vol. 13, No. 6, ("Pediacyl") Jun. 1961, p. 60i, (2)(1960), p. 33f, Prefacose, (3), vol. 24, No. 4, Apr. 1972, p. 56d, Efferalgan and (4) vol. 21, No. 10, Oct. 1969, p. 157H, Patmin.
Chem. Abst. Chemical Substance Index A-B, vol. 86, under Acetamide, N-OH phenyl.
Chem. Abst. vol. 67, 52498w.

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