Thrombin-binding protein substance and process for preparing the

Details Thrombin-binding protein substance and process for preparing the Thrombin-binding protein substance and process for preparing the

1989-08-16

1991-08-27

Schain, Howard E.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530413, 530395, 530834, 514 8, 514 21, 435 701, 435 703, C07K 320, C07K 328, C07K 1506, C07K 1514

Patent

active

050434250

ABSTRACT:
Novel thrombin-binding substances (A) and (B) are disclosed. The thrombin-binding substances have the following characteristics:

REFERENCES:
patent: 4748156 (1988-05-01), Aoki et al.
The Journal of Biological Chemistry, vol. 259, No. 19, Oct. 1984, H. H. Salem et al, pp. 12246-12251.
Thrombosis Research, vol. 37, 1985, pp. 353-364, S. Kurosaw et al.
Biological Abstracts, vol. 81, 1986, Abstract No. 91313, H. Ishii et al.
The Embo Journal, vol. 6, No. 7, 1987, pp. 1891-1897, K. Suzuki.
The Journal of Biological Chemistry, 1984, pp. 12246-12251, vol. 259, No. 19, Hatem H. Salem, et al., "Isolation and Characterization of Thrombomodulin from Human Placenta".
J. Clin. Invest., vol. 76, Dec. 1985, pp. 2178-2181, Hidemi Ishii et al., "Thrombomodulin is Present in Human Plasma and Urine".

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