Clindamycin phosphate synthesis

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 162, C07M 1104

Patent

active

051823748

ABSTRACT:
An improved process for producing the antibiotic compound clindamycin phosphate through the use of novel intermediate, 7(S)-chloro-7-deoxylincomycin-2-bis(2,2,2-trichloroethyl)phosphochloridate and similar compounds.

REFERENCES:
patent: 3487068 (1969-12-01), Morozowich et al.
patent: 4686208 (1987-08-01), Lockhoft et al.
patent: 4849515 (1989-07-01), Matier et al.

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