Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-12-22
1996-03-05
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514364, 548136, 548144, C07D41310, A61K 3141
Patent
active
054968356
ABSTRACT:
This invention relates to a compound represented by the formula ##STR1## wherein the ring A stands for a 5-10 membered aromatic heterocyclic group optionally having, besides R.sup.1 and R.sup.2, further substituents; R.sup.1 stands for an optionally substituted hydrocarbon residue which is optionally bonded through a hetero-atom; R.sup.2 stands for a group capable of liberating proton in a living body or a group convertible thereinto; R.sup.3 stands for an 5-7 membered optionally substituted heterocyclic residue having, as a group capable of constituting the ring, carbonyl group, thiocarbonyl group, an optionally oxidized sulfur atom or a group convertible into them; X shows that the ring Y and the ring W are bonded to each other directly or through a spacer having an atomic length of two or less; the ring W and the ring Y are each an optionally substituted aromatic hydrocarbon or aromatic heterocyclic residue; and n denotes an integer of 1 to 3, or a salt thereof and to an angiotensin II antagonistic agent containing the compound (I) or a salt thereof.
REFERENCES:
patent: 5243054 (1993-09-01), Naka
Inada Yoshiyuki
Kubo Keiji
Naka Takehiko
Gerstl Robert
Takeda Chemical Industries Ltd.
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