Piperidylidene derivatives of carboxy-5H-dibenzo[a,d]cyclohepten

Details Piperidylidene derivatives of carboxy-5H-dibenzo[a,d]cyclohepten Piperidylidene derivatives of carboxy-5H-dibenzo[a,d]cyclohepten

1974-06-05

1976-09-21

Todd, G. Thomas

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424267, C07D21178

Patent

active

039818772

ABSTRACT:
The new 1-alkyl-4-(1, 2, or 3-carboxy-5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidine compounds are prepared from the corresponding 1, 2 or 3-carboxy-5H-dibenzo[a,d]cyclohepten-5-one by reaction with a Grignard reagent prepared from a 1-alkyl-4-halo piperidine to form an intermediate carbinol, or a 1, 2 or 3-carboxy-5-(1-alkyl-4-piperidyl)-5H-dibenzo[a,d]cyclohepten-5-ol which is then dehydrated to produce the desired 1-alkyl-4-(1, 2 or 3-carboxy-5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidine, or alternatively by hydrolysis of a 1-alkyl-4-(1, 2 or 3-cyano-5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidine compound to form the corresponding 1-alkyl-4-(1, 2 or 3-carboxy-5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidine compound.

REFERENCES:
patent: 3014911 (1961-12-01), Engelhardt
patent: 3511881 (1970-05-01), Hoffsommer et al.
patent: 3547980 (1970-12-01), Engelhardt et al.
Migridichian, "Organic Synthesis, vol. 1," Reinhold Publishing Corp., New York (1957), pp. 420-423.
Morrison et al., "Organic Chemistry, 2nd Ed.", Allyn and Bacon, Inc., Boston (1966), 777.

Affiliated with

Also associated with

Rating

Piperidylidene derivatives of carboxy-5H-dibenzo[a,d]cyclohepten does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Piperidylidene derivatives of carboxy-5H-dibenzo[a,d]cyclohepten, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Piperidylidene derivatives of carboxy-5H-dibenzo[a,d]cyclohepten will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1412920