Penicillin monoesters, their production and intermediates thereo

Details Penicillin monoesters, their production and intermediates thereo Penicillin monoesters, their production and intermediates thereo

1973-09-21

1976-09-21

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424271, C07D49912, C07D49972

Patent

active

039818667

ABSTRACT:
Mono-esters of .alpha.-carboxypenicillins and their preparation are described including intermediates for the mono-esters. The mono-esters are esterified on the .alpha.-carboxy group. They are well absorbed orally and de-esterified in vivo to give high serum concentrations of the parent .alpha.-carboxypenicillins.

REFERENCES:
patent: 3647783 (1972-03-01), Oirie
patent: 3697507 (1972-10-01), Frederiksen et al.
patent: 3847913 (1974-11-01), Gudtfredsen
patent: 3864340 (1975-02-01), Ishimaru et al.
patent: 3925372 (1975-12-01), Chauvette

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