Dihydro-4(hydroxyalkyeneamino)quinolines

Details Dihydro-4(hydroxyalkyeneamino)quinolines Dihydro-4(hydroxyalkyeneamino)quinolines

1990-05-10

1993-01-26

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142352, 514313, 544 60, 544 61, 544128, 544101, 546159, 546162, A61K 3154, A61K 31535, A61K 3147, C07D29506

Patent

active

051822750

ABSTRACT:
There are disclosed novel compounds of the formula ##STR1## where X is hydrogen, loweralkyl, loweralkoxy, hydroxy, halogen, nitro or trifluoromethyl; R.sub.1 is hydrogen or loweralkyl; R.sub.2 is hydrogen, loweralkyl, arylloweralkyl or --(CH.sub.2).sub.m R.sub.7 wherein m is 1, 2 or 3 and R.sub.7 is cyano or amino; R.sub.3 and R.sub.4 are independently hydrogen or loweralkyl; R.sub.5 and R.sub.6 are independently hydrogen or loweralkyl, or R.sub.5 +R.sub.6 taken together with the carbon atom to which they are attached constitute a cyclobutane, cyclopentane, cyclohexane, cycloheptane, pyrrolidine, piperidine, morpholine or thiomorpholine ring, or R.sub.5 is hydrogen and R.sub.6 is aryl or --CH.sub.2 OR.sub.8 wherein R.sub.8 is hydrogen, loweralkyl or loweralkylcarbonyl, which are useful for enhancing memory.

REFERENCES:
patent: 3957751 (1976-05-01), Simpson
Abbasi et al. J. Heterocyclic. Chem. 1978 15(4), 649-53 Chemical Abstracts. vol. 90, 1979 Abstract 6324p.

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