Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1989-02-22
1992-05-05
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 25, 514 53, 514557, 514689, 514733, 514859, 514864, A61K 3170, A61K 31045, A61K 3112, A61K 3119
Patent
active
051108011
ABSTRACT:
Acne is treated by administering to the subject a substance which is effective in blocking glucose entry into sebaceous cells, thereby inhibiting the production of sebum by these cells. Typically, the substance is administered topically and is dissolved or suspended in an appropriate solvent. The preferred substance is phloretin, which can for example, be dissolved in propylene glycol.
REFERENCES:
patent: 3006810 (1961-10-01), Shinn et al.
patent: 3006811 (1961-10-01), Shinn et al.
patent: 3085933 (1963-04-01), Schooley et al.
patent: 3272702 (1966-09-01), Schooley et al.
patent: 3523937 (1970-08-01), Biegeleisen
patent: 4272508 (1981-06-01), Tamm
patent: 4326055 (1982-04-01), Loeligek
patent: 4367227 (1983-01-01), Bingham
patent: 4456620 (1984-06-01), Laurent et al.
patent: 4473551 (1984-09-01), Schinitsky
patent: 4507287 (1985-03-01), Dixon
patent: 4565806 (1986-01-01), Setala
patent: 4565863 (1986-01-01), Bollag et al.
patent: 4588750 (1986-05-01), Boris
patent: 4657901 (1987-04-01), Ueda et al.
patent: 4684627 (1987-08-01), Leveen et al.
patent: 4814324 (1989-03-01), Borris et al.
Lazo et al.; Febs Letters 98 (1): 88-90, (Feb. 1979).
Arita, et al.; J. Biochem. 88 (5): 1399-1406 (1980).
Holstege et al.; Eur. J. Biochem. 121: 469-474 (1982).
The Merck Manual; 15th Ed.; Berkow et al., Eds. pp. 2277-2280 Publ. Merck, Sharp & Dohme Research Labs (1987).
Yamamura et al.; Chemical Abstracts 86:169357h (1977).
Noda Shokkin Kogyo; Chemical Abstracts 100:33273c (1984).
The Merck Manual; 15th Ed. pp. 2265-2266 (1987).
Shamberev et al.; Chemical Abstracts 71:120110y (1969).
Glass; Chemical Abstracts 93:210243c (1980).
Chemical Abstracts, vol. 67, 115099q, 1967, Evidence for Carrier-Mediated Transport of Monosaccharides in the Ehrlich Ascites Tumor Cell, Kolber et al.
Chemical Abstracts, vol. 73, 12924q. 1970, Effect of Glucose and ATP on the Respiration of Ascitic Cancerous Cells in the Presence of Phlorizin and Ouabain, Ilinich et al.
Dialog Information Service, Embase 74-79, 77012446, Kinetics of 2-Deoxy-D-Glucose Transport into Cultured Mouse Neuroblastoma Cells, Walum et al.
Dialog Information Service, Embase 80-81, 81246326, The Hexose Transport System in the Human K-562 Chronic Myelogenous Leukemia Derived Cell, Dozier et al.
Dialog Information Service, Data Base 72, Embase 82-88, 86187256, Decrease in Glucose Transport Activity of Friend Erythroleukemia Cell Caused by Dimethylsulfoxide, a Differentiation-Inducing Reagent, Kasahara et al.
Dialong Information Service, Data Base 72, Embase 82-88, 86199919, Effects of Insulin on Glucose Transporters and Metabolic Patterns in Harding-Passey Melanoma Cells, Delicado et al.
LeVeen Harry H.
LeVeen Robert F.
Brown Johnnie R.
Carson Nancy S.
Hale John S.
LandOfFree
Treatment of acne does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Treatment of acne, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of acne will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1412518