Calcium polycarbophil-alginate controlled release composition an

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices

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424484, 424488, 424479, 424482, 424422, 424427, 424430, 424434, 424435, 424436, 424457, 424470, 424479, 424482, 424461, 424462, 424443, 424499, 424501, A61K 4732, A61K 4736, A61K 910, A61K 916

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active

051106051

ABSTRACT:
A polymeric complex composition comprising a reaction complex formed by the interaction of a polycarbophil component with alginic acid or a salt thereof, said interaction being performed in the presence of a divalent cation and in the presence of an active agent selected from the group consisting of medicinal agents and cosmetic agents. There is also described a method of controlled release treatment comprising the steps of providing such a polymeric complex and an effective amount of an active agent selected from the group consisting of medicinal agents and cosmetic agents contained within said complex, and contacting an area of skin or mucous membrane to be treated with said composition for a sufficient period of time allow a therapeutically effective amount of said active agent to be released from the complex.

REFERENCES:
patent: 3640741 (1972-02-01), Etes
patent: 4029815 (1977-06-01), Sherlock et al.
patent: 4140763 (1979-02-01), Bachrach et al.
patent: 4615697 (1986-10-01), Robinson
patent: 4867979 (1989-09-01), Sheth et al.
patent: 4900552 (1990-02-01), Saavordeker et al.
patent: 4988679 (1991-01-01), Chavkin et al.

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