Reducing fluorescent background in fluorescent immunoassays

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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23230B, 250302, 424 7, 424 11, 424 12, 424 13, 435 7, G01N 3352, G01N 100

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active

042527830

ABSTRACT:
Background fluorescence which interferes with the measurement of an analyte in fluorescent immunoassays in serum samples is substantially diminished by treating the serum sample with a sufficient amount of a peroxidic compound, either organic or inorganic, for a time sufficient to reduce the background fluorescence contributed by serum components. The peroxidic compound is readily quenched, without adversely affecting the assay composition.

REFERENCES:
patent: 3689633 (1972-09-01), Sanae
patent: 4121975 (1978-10-01), Ullman

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