Prolonged release drug form for the treatment of bovine mastitis

Details Prolonged release drug form for the treatment of bovine mastitis Prolonged release drug form for the treatment of bovine mastitis

1975-06-25

1977-03-08

Rosen, Sam

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424115, 424116, 424227, A61K 31765, A61K 3566

Patent

active

040113124

ABSTRACT:
A prolonged release drug dosage form for the treatment of bovine mastitis, specifically suited for dry cow treatment, consists of an antimicrobial agent dispersed in a matrix of a low molecular weight polyester of glycolic and lactic acids, and shaped as a cylindrical bougie for facile insertion into the teat canal. Said polyester erodes by hydrolysis in the bioenvironment, providing a continuous release of the medication throughout the desired duration of the treatment. The low molecular weight polyesters have a glycolic acid content of about 60 to 80 mole percent, a lactic acid content of about 20 to 40 mole percent, and a molecular weight less than 2000.

REFERENCES:
patent: 3755558 (1973-08-01), Scribner
patent: 3773919 (1973-11-01), Boswell et al.
patent: 3887699 (1975-06-01), Yolles

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