Hydrazones

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514582, 514590, 514631, 514639, 564 19, 564 36, 564225, 564226, 564227, 564228, A61K 3115, A61K 31155, C07C28116

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active

053958551

ABSTRACT:
Compounds of formula I ##STR1## wherein A, X, Z and R.sub.1 -R.sub.5 are as defined in the description, and their salts have valuable pharmaceutical properties and are effective especially against tumors. They are prepared in a manner known per se.

REFERENCES:
patent: 4076726 (1978-02-01), Panneman et al.
patent: 4971986 (1990-11-01), Stanek et al.
Chem Abstr. 104:207159v (1986) Corresponding to AM above.
Chem Abstr. 109:92791d (1987) Corresponding to AM above.
Chem Abstr. 1958, 14678a Corresponding to AP above.
Chem Abstr. 105:6283c (1985).
Misra, et al, J. Indian Chem. Soc. vol. 52, Oct. 1975, pp. 981-982 Synthesis and Antibacterial Activity of Thiosemic Arbazones and Hydrazones Derived From Indanone-1.
Chem Abstr. 107:77634v (1987).
Sam et al, J. Pharmacol. Sci. 53, 1364-1368 (1965) Potential Anti Neoplastic Agents Derived from 1,2-Epoxyindan.
Chatterjea et al; J. Indian Chem. Soc. 37, No. 8, 1960, 443-450 "The Course of Cyclisation of .alpha.-Benzylhomophthalic Acids".

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