Compositions – Nonreactive analytical – testing – or indicating compositions
Patent
1976-08-02
1978-02-07
Padgett, Benjamin R.
Compositions
Nonreactive analytical, testing, or indicating compositions
23230B, 1951035R, 356 39, 424 7, C09K 300, G01N 3106, G01N 3122, G01N 3316
Patent
active
040726274
ABSTRACT:
An aqueous solution useful in connection with a redox type spectrophotometric or colorimetric determination of uric acid in a biologic fluid is disclosed. The solution contains either a multivalent metallic ion reducible to a lower valence state by uric acid, a water soluble chelating compound capable of complexing with a metallic ion after reduction by uric acid to yield, in complexed form, a colored complex, or a combination of said ion and said chelating compound. The solution also contains, as an added constituent, imidazole, an alpha-amino acid, or a combination thereof. This constituent is present in an amount such that, when said solution contains a biologic fluid containing protein and uric acid, a buffer system such that the pH of the solution is 6 to 12, and a multivalent metal ion, the protein in the fluid does not significantly reduce said multivalent ions present in the solution.
REFERENCES:
patent: 3282649 (1966-11-01), Bittner
patent: 3528777 (1970-09-01), Moran
patent: 3536448 (1970-10-01), Patel
patent: 3649198 (1972-03-01), Rush
patent: 3711252 (1973-01-01), Roy
patent: 3794467 (1974-02-01), Adams et al.
patent: 3822115 (1974-07-01), Morin et al.
patent: 3920400 (1975-11-01), Schreibe et al.
patent: 3928137 (1975-12-01), Monte et al.
Mopper, K., et al., Anal. Biochem., vol. 56, pp. 440-442 (1973).
Gindler, E. M., Clinical Chemistry, vol. 16, No. 6, p. 519 (1970).
Gron T. S.
Padgett Benjamin R.
Pierce Chemical Company
LandOfFree
Uric acid determination does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Uric acid determination, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Uric acid determination will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1400116