Methods and compositions for the treatment of lung conditions

Details Methods and compositions for the treatment of lung conditions Methods and compositions for the treatment of lung conditions

1987-08-07

1990-07-31

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

Interferon

424 851, A61K 3766, A61K 3700

Patent

active

049449419

ABSTRACT:
Disclosed are improved methods for the treatment of lung membrane diseases such as respiratory distress syndrome (RDS) or idiopathic RDS, employing compositions including therapeutically effective amounts of gamma interferon and/or tumor necrosis factor (TNF), each alone or in combination with corticosteroids, preferably employing recombinant human gamma interferon and/or TNF. Individuals, including adults or children, are administered amounts of these agents that are generally effective to induce the lungs of affected individuals to produce one or more surfactant components, including both phospholipid and surfactant protein substituents.

REFERENCES:
patent: 4522811 (1985-06-01), Eppstein et al.
patent: 4650674 (1987-03-01), Aggarwa et al.
patent: 4762791 (1988-08-01), Goeddel et al.
patent: 4774085 (1988-09-01), Fidler

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