Prostaglandins of the F series

Details Prostaglandins of the F series Prostaglandins of the F series

1996-08-23

1998-06-23

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560121, 562463, 562503, C07C40500

Patent

active

057707596

ABSTRACT:
The present invention provides new compounds, 13,14-dihydro-15-keto-PGFs, and vassopressors containing them, which raise blood pressure without substantial ephemeral depression of blood pressure, trachea or enteron contraction effect inherent in usual PGFs.

REFERENCES:
patent: 3896156 (1975-07-01), Beal, III et al.
patent: 4128713 (1978-12-01), Schneider et al.
patent: 4131738 (1978-12-01), Smith
patent: 4158667 (1979-06-01), Axen
C.R. Pace-Asiak et al., "Application of Prostaglandin-Profiling Techniques to Study the Release of Prostaglandins from the Fetal Lamb Ductus Arteriosus," Biochimica et Biophysica Acta 750(1983)330-333.
M. Rigaud et al., "In Vitro Inhibition of Human Lymphocyte Transformation by Natural or Synthetic Prostaglandins," Prostaglandins and Medicine 3:167-172, 1979.
Acta Pharmaceutica Sinica, vol. 16, No. 5 (May 1981).
Jones, Advances in Prostor Thromb. Res. 1 221-230 (1976).

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