Tissue fractions of sea cucumber for the treatment of inflammati

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex

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536 41, A01N 6500, C07G 300

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active

057702055

ABSTRACT:
The present invention relates to fractions of sea cucumbers (Phylum Echinodermata, Class Holothuroidea), particularly those derived from the epithelial layers and the flower portion, that markedly inhibit inflammation in laboratory animals and show significant subjective benefit in humans with inflammation disorders such as arthritis, and methods for preparing the same.

REFERENCES:
Yaacob et al. Malaysian Applied Biology 24(1) pp. 23-28, 1995.
Eylers, John P., Ion-Dependent Viscosity of Holothurian Body Wall and Its Implications for the Functional Morphology of Echinoderms. J. Exp. Biol., 99:1-8 (1982).
Findlay, John A., Frondogenin, A New Aglycone From the Sea Cucumber Cucumaria Frondosa. J. Natural Prod., 47(2):320-324, Mar.-Apr.(1984).
Robert, Andre et al., The Granuloma Pouch as a Routine Assay for Antiphlogistic Compounds. Acta Endocrinologica, 25:105-112 (1957).

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