Process for production of methyl 2-tetradecylgycidate

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549549, C07D30102

Patent

active

044992947

ABSTRACT:
An improved process for producing the hypoglycemic compound, methyl 2-tetradecylglycidate, by reacting methyl .alpha.-chloropalmitate with lithium methoxide in the presence of formaldehyde in a dipolar aprotic solvent such as DMF or DMSO.

REFERENCES:
patent: 2939872 (1960-06-01), Hudson
patent: 3506690 (1970-04-01), Normant et al.
patent: 3933864 (1976-01-01), White
patent: 4196300 (1980-04-01), Mohrbacher et al.
A. Weissberger, Heterocyclic Compounds with Three- and Four- Membered Rings, Part One (1964) Interscience publishers, N.Y., p. 113.

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