Computer-aided engineering system for design of sequence arrays

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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430 5, 4352872, 536 243, 536 253, 935 88, C12Q 168, C07H 2104, G03F 900

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active

055938396

ABSTRACT:
An improved set of computer tools for forming arrays. According to one aspect of the invention, a computer system is used to select probes and design the layout of an array of DNA or other polymers with certain beneficial characteristics. According to another aspect of the invention, a computer system uses chip design files to design and/or generate lithographic masks.

REFERENCES:
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5235626 (1993-08-01), Flamholz et al.
patent: 5288514 (1994-02-01), Ellman
USSN 08/143,312 filed Oct. 26, 1993, entitled "Arrays of Nucleic Acid Probes on Biological Chips."
Fodor et al. "Light-Directed, Spatially Addressable Parallel Chemical Synthesis," Science (1991) 251:767-773.
Brown et al., "An Inexpensive MSI/LSI Mask Making System," Symposium Proceedings University Government Industry Microelectronics Symposium, pp. III-31 to III-38 (1981).

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