Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-05
1997-05-13
Fox, David T.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 694, 435 6951, 435 701, 4351723, 536 235, 536 2352, 800205, 800DIG43, C12N 1512, C12N 1520, C12N 1582, C12N 504
Patent
active
056291752
ABSTRACT:
Novel constructs are provided for expression of physiologically active mammalian proteins in plant cells, either in culture or under cultivation. The constructs provide a promoter functional in a plant host, a structural gene coding for mammalian protein and a terminator functional in a plant host. The construct is introduced into a plant cell to become integrated into the plant genome for expression in the plant cells or plants. The plant cells may be harvested and the mammalian protein isolated in physiologically active form.
REFERENCES:
patent: 4399216 (1983-08-01), Axel et al.
patent: 4530901 (1985-07-01), Weissman
patent: 4956282 (1990-09-01), Goodman et al.
patent: 5550038 (1996-08-01), Goodman et al.
Lefebvre, et al., "Mammalian Metallothione in Functions in Plants", Biotechnology, Canada, (1987), vol. 5:1053-1056.
Sijmons, et al., "Production of Correctly Processed Human Serum Albumin in Transgenic Plants", Biotechnology, The Netherlands, (1990), vol. 8:217-221.
Hiatt, et al., "Production of Antibodies in Transgenic Plants", Biotechnology, La Jolla, California (1989) vol. 342:77-78.
Odell, et al., "Identification of DNA Sequences Required for Activity of The Cauliflower Mosaic Virus 35S Promoter" New York (1985), vol. 313:810-812.
Herrera-Estrella, et al., "Agrobacterium as a Vector System for the Introduction of Genes into Plants", Plant Genetic Engineering, Cambridge Press, University, (1985), New York, pp. 61-93.
Fraley, et al., Biotechnology (1985) 3:629-635.
Odell, et al., Nature (1985) 313:810-812.
Velten, et al., EMBO (1984) 3:2723-2730.
Leemans, et al., Molecular Biology of Plant Tumors (1982) Academic Press, New York pp. 537-545.
Jaynes and Strobel, International review of Cytology (1981) Supp 13:105-125.
Depicker et al., Genetic Engineering of Plant Cells-An Agr. Persp. (1983) Plenum Press, New York pp. 4803-4807.
Fraley, et al., Proc. Natl. Acad. Sci. USA (1983) 80:4803-4807.
Shaw, et al., Gene (1983) 23:315-330.
Tuite M. F., et al., "Regulated high efficiency expression of human interferon-alpha in Saccharomyces cerevisiae" (1982) The EMBO Journal 1:603-608.
Rogers, S. C., et al., "Investigation of Factors Involved in Foreign Protein Expression in Transformed Plants". Biotechnology in Plant Science (1985) pp. 219-227.
Gray, P. W. et al., Proc. Natl. Acad. Sci, USA vol. 80:5842-5846 (1983).
Odell, J. T., et al, "Identification of DNA sequences required for activity of the cauliflower mosaic virus 35S promoter", Nature, vol. 313:810-812.
Eichboltz, D., et al., Somatic Cell and Molecular Genetics vol. 13:67-76 (1987).
Yip, Y.K., et al. Proc. Natl. Acad. Sci. USA Biochemistry vol. 79:1820-1824 (1982).
Stryer L. page 719-720.
Comai Luca
Goodman Robert M.
Houck Catherine M.
Knauf Vic C.
Calgene Inc.
Fox David T.
LandOfFree
Molecular farming does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Molecular farming, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Molecular farming will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1384489