Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1984-04-03
1987-09-15
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Lymphokine
A61K 39155, A61K 39295
Patent
active
046938931
ABSTRACT:
It is known that the human influenza virus strain A/Puerto Rico/8/34 grows particularly well in eggs and that reassorted viruses having it as a parent may also grow well in eggs. It has now been found that certain reassortants of A/PR/8/34 and equine influenza viruses, namely those which comprise the RNA7 segment from A/PR/8/34, will grow in cell culture, even though the parent equine influenza vius will not.
Thus the specification describes and claims: reassorted viruses comprising genes for surface antigens of equine influenza viruses and the RNA7 segment from A/PR/8/34; methods of obtaining such viruses by reassortment; methods of propagating such reassorted viruses in cell culture, especially Vero cells; vaccines against equine influenza comprising such reassorted viruses; and methods of vaccinating equines against influenza.
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Brown Don A. L. D.
Burroughs Wellcome
Rose Shep K.
Williams Gregory D.
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