Rapid, high capacity nucleic acid based assay

Details Rapid, high capacity nucleic acid based assay Rapid, high capacity nucleic acid based assay

1994-04-21

1998-03-10

Zitomer, Stephanie W.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 6, 935 77, C12Q 170, C12Q 168

Patent

active

057260125

ABSTRACT:
A rapid, high capacity method using chaotropic agents for evaluating nucleic acids is described. Samples containing the target nucleic acid can be evaluated in a nucleic acid based sandwich hybridization assay which is performed, in part, in a chaotropic solution which is removed prior to detecting and/or quantitating the product. This assay can be used to detect and/or quantitate nucleic acid levels. It can also be used as an infectivity assay and/or as an assay to evaluate anti-infectious agent activity of compounds.

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