Method for detection of susceptibility mutations for ototoxic de

Details Method for detection of susceptibility mutations for ototoxic de Method for detection of susceptibility mutations for ototoxic de

1993-06-30

1996-04-09

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 536 2431, 935 77, 935 78, C12Q 168, C12P 1934, C07H 2104

Patent

active

055061010

ABSTRACT:
Method for detection of mitochondrial nucleotide associated with predisposition for ototoxic deafness, especially deafness associated with the administration of aminoglycosides, is described.

REFERENCES:
Prezant et al. (1992) American J. Medical Genetics 44:465-472.
Higashi et al. (1989) Clin. Genet. 35:433-436.
Hu et al. (1991) J. Med. Genet. 28:79-83.
Bu, X et al. (1993) Genet. Epidem. 10(1):3-15.
Moazed et al. (1987) Nature 327:389-394.

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