Diaryl 5,6-fused heterocyclic acids as leukotriene antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514249, 514258, 514301, 514302, 544184, 544255, 544278, 544350, 546114, 546115, 546116, A61K 31435, C07D49504, C07D51304, C07D491048

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active

054729645

ABSTRACT:
Compounds having the formula I: ##STR1## are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

REFERENCES:
patent: 4794188 (1988-12-01), Musser et al.
patent: 4957932 (1990-09-01), Young et al.

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