Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-03-31
1999-04-06
Walsh, Stephen
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
4353201, 435 691, 530350, C12N 1512, C12N 1563, G07K 14705
Patent
active
058920188
ABSTRACT:
The present invention discloses a novel subfamily of amiloride sensitive sodium channel proteins isolated and purified from the human central nervous system. DNA sequences encoding such proteins are disclosed as are methods and procedures for development of pharmacologic agents for treatment of diseases associated with central nervous system dysfunction.
REFERENCES:
Waldmann, et al. J. Biol. Chem. vol. 271(18): pp. 10433-10436, May 1996.
Price et al. J. Biol. Chem. vol. 271(14): pp. 7879-7882, Apr. 1996.
Kriegler, M. in Gene Transfer and Expression: A Laboratory Manual, pp. 3-176, Stockton Press, NY, New York, 1990.
Price Margaret P.
Welsh Michael J.
Basham Daryl A.
Walsh Stephen
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