Spiro-heteroazalones for treatment of diabetic complications

Details Spiro-heteroazalones for treatment of diabetic complications Spiro-heteroazalones for treatment of diabetic complications

1990-07-12

1991-11-19

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 15, A61K 3141, C07D47110

Patent

active

050666592

ABSTRACT:
Spiro-heteroazolones are disclosed which are useful as aldose reductase inhibitors and as therapeutic agents for the treatment of complications arising from diabetes. Pharmaceutical compositions containing the spiro compounds and a method of treating diabetic complications are also disclosed.

REFERENCES:
patent: 4117230 (1978-09-01), Sarges
patent: 4147795 (1979-04-01), Sarges
patent: 4210756 (1980-07-01), Sarges
patent: 4282229 (1981-08-01), Sarges
patent: 4283409 (1981-08-01), Belletire et al.
patent: 4540704 (1985-09-01), Ueda et al.

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