Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-02-07
1991-11-19
Shen, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514274, 514392, 514863, 544318, 544298, 548307, A61K 31505, A61K 31415, C07D23902, C07D23530
Patent
active
050666584
ABSTRACT:
The present invention relates to substituted hydroxyureas. These compounds inhibit the enzyme 5-lipoxygenase. In addition, certain of the compounds also inhibit the enzyme-cyclooxygenase. The compounds are useful for treating asthma, allergies, arthritis, posoriasis, ischemia, dermatitis, inflammation and/or broncho-constriction and/or inflammatory diseases of the eye.
REFERENCES:
patent: 4618692 (1986-10-01), Scheffler et al.
Chou et al., CA87-83966q (1977).
Sulsky et al., Chem. Abst. 112-216835e (1990).
Demers James P.
Sulsky Richard B.
Lambert Benjamin F.
Ortho Pharmaceutical Corporation
Shen Cecilia
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