Enantiomers of 1-[(4-chlorophenyl)phenylmethyl]-4-[(4-methylphen

Details Enantiomers of 1-[(4-chlorophenyl)phenylmethyl]-4-[(4-methylphen Enantiomers of 1-[(4-chlorophenyl)phenylmethyl]-4-[(4-methylphen

Filed on

1994-03-08

Date issued

1995-12-26

Examiner

Bernhardt, Emily

Patent Class

Organic compounds -- part of the class 532-570 series

SubClass

Organic compounds

SubSubClass

Nitrogen attached directly or indirectly to the purine ring...

Other Related Categories

544396, 564 90, 564321, C07D29526, C07D295088, C07D295073, C07D295104

Type

Patent

Status

active

Patent number

054789419

Description

ABSTRACT:
Levorotatory and dextrorotatory enantiomers of 1-[(4-chlorophenyl)phenylmethyl]-4-[(4-methylphenyl)sulfonyl]piperazine of the formula ##STR1## their preparation and use for the preparation of substantially optically pure enantiomers of 1-[(4-chlorophenyl)phenylmethyl]piperazine, which are themselves valuable intermediate products for the preparation of optically active therapeutic compounds having a very high degree of optical purity.

REFERENCES:
patent: 3406174 (1968-10-01), Houlihan
patent: 4525358 (1985-06-01), Baltes et al.
patent: 4968676 (1990-11-01), Zipperer et al.
patent: 5087627 (1992-02-01), Morita et al.
Kato et al, Chemical Abstracts, vol. 78, No. 148000 (1973).

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