Method providing enhanced chemiluminescence from 1,2-dioxetanes

Details Method providing enhanced chemiluminescence from 1,2-dioxetanes Method providing enhanced chemiluminescence from 1,2-dioxetanes

1993-02-22

1999-04-06

Marschel, Ardin H.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 5, 435 71, 435 72, 436501, 935 77, 935 78, C12Q 168

Patent

active

058916261

ABSTRACT:
A method and compositions including a 1,2-dioxetane and a fluorescent compound is described. In particular, enzymatic triggering of a triggerable 1,2-dioxetane admixed with a surfactant and the fluorescent compound attached to a hydrocarbon to provide a co-surfactant in a micelle or other structure providing close association of these molecules is described. The method and compositions are useful in immunoassays and in DNA probes used for various purposes.

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