Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1987-09-01
1989-02-28
Ford, John M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D23354
Patent
active
048087262
ABSTRACT:
N-cyano-N'-methyl-N"-(2-(5-methyl-4-imidazolylmethylthio)ethyl)guanidine (Cimetidine), which is valuable as an agent for controlling secretion of gastric acid, is prepared in a high yield by reacting N-cyano-N'-methyl-N"-(2-(butane-2,3-dionyl)thioethyl)-guanidine as the starting compound with an ammonium salt of a carboxylic acid and formaldehyde.
REFERENCES:
patent: 4602093 (1986-07-01), Baldwin et al.
Hashimoto Isao
Kato Houji
Kihara Noriaki
Mukaiyama Teruaki
Tomino Ikuo
Ford John M.
Mitsui Petrochemical Industries Ltd.
Whittenbaugh Robert C.
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