Aqueous pharmaceutical formulations of sodium cromoglycate

Details Aqueous pharmaceutical formulations of sodium cromoglycate Aqueous pharmaceutical formulations of sodium cromoglycate

1994-07-28

1995-12-12

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514738, 514772, A61K 3135, A61K 31045, A61K 4700

Patent

active

054750237

ABSTRACT:
A pharmaceutical formulation comprising a substantially clear aqueous solution having a viscosity of less than 10 mPa.s containing 3.5 to 5% w/v of 1,3-bis(2-carboxychromon-5-yloxy)-propan-2-ol, or a pharmaceutically acceptable salt thereof, as active ingredient and glycerol, the concentration of ions of metals of groups IIA, IB, IIB and IVB of the periodic table or of transition metals being less than 20 ppm.

REFERENCES:
patent: 3975536 (1976-08-01), Stevenson et al.
patent: 4053628 (1977-10-01), Stevenson et al.
Research Disclosures 318, pp. 832-833 (No. 31850) Oct. 1990 (Anonymous).
Drug Design and Delivery, 1987, vol. 1, pp. 285-295, "Enhanced Percutaneous Absorption of Ionizable Water-soluble Drugs."
Journal of Pharmaceutical Sciences, Jan. 1988, vol. 77, No. 1, pp. 3-14, "Mechanisms of Corneal Drug Penetration I: In Vivo and In Vitro Kinetics."

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