Anti-cancer compositions for delivering 5-fluorouracil

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514 50, A61K 31505, A61K 3170

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active

049141058

ABSTRACT:
An anti-cancer composition which comprises at least one 5-fluorouracil derivative, and a uracil derivative.

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patent: 4481203 (1984-11-01), Fujii et al.
patent: 4507301 (1985-03-01), Fujii et al.
Chemical Abstracts, 92:47236w(1980).
Fujii et al., 99412t, Chemical Abstracts, vol. 81, pp. 32-33, (1974).
Burchenal, J., et al., "Studies on the Synergism of Fluorinated Pyrimidines and Certain Pyrimide and Purine Derivatives Against Transplanted Mouse Leukemia", Cancer Chemotherapy Rpts. 6, pp. 1-5, (1960).
Jato, J. et al., "5-Fluorouracial and Derivatives in Cancer Chemotheraphy III", Journal of Pharmaceutical Sciences, vol. 62, No. 12, pp. 1975-1977, (1973).
Jato, J., et al., "Effect of Deoxyuridine Coadministration on Toxicity and Antitumor Activity of Fluorouracil and Floxuridine", Journal of Pharmaceutical Sciences, vol. 64, No. 6, pp. 943-946, (1975).

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