Substituted quinolyl compounds exhibiting selective leukotriene

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514312, 514313, 514314, 546155, 546156, 546157, 546159, 546162, 546167, 546169, 546173, 546175, 546176, 546177, 546179, 546180, A61K 3147, C07D21514, C07D215227, C07D21538

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active

054929156

ABSTRACT:
This invention relates to compounds having selective LTB.sub.4 antagonist properties. Therapeutic compositions comprising said compounds and methods for the treatment of disorders involving LTB.sub.4 agonist-mediated activity utilizing said compositions wherein the compounds are described by the formula ##STR1## wherein R.sub.4, X, R, Y, R', Q, m and n are herein defined, and pharmaceutically acceptable salts thereof.

REFERENCES:
Kaihara et al., Arch. Biochem., Biophys. 110(2), 316-19 (1965).

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