Triazolopyridazine derivatives, their production and use

Details Triazolopyridazine derivatives, their production and use Triazolopyridazine derivatives, their production and use

1994-04-12

1996-02-20

Bernhardt, Emily

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514248, 544115, 544118, 544234, 544236, 564 95, A61K 3150, A61K 31535, C07D48704, C07D48714

Patent

active

054929091

ABSTRACT:
A compound of the formula: ##STR1## wherein R.sup.1 is a hydrogen atom, a lower alkyl group or a halogen atom; R.sup.2 and R.sup.3 are a hydrogen atom, a lower alkyl group or a 5- to 7-membered cyclic group formed together with the adjacent --C.dbd.C--; X is an oxygen atom, a sulfur atom or a methylene group; Y is an optionally substituted methylene group, a divalent 3- to 7-membered homo- or heterocyclic group; R.sup.6 and R.sup.7 are a hydrogen atom, a lower alkyl group, a cycloalkyl group, an aryl group, or a nitrogen-containing heterocyclic group formed together With the adjacent nitrogen atom; m is an integer of 0 to 4; and n is an integer of 0 to 4, or a salt thereof. Said compound has an excellent anti-PAF activity, antiallergic action, etc., thus is useful as an antiasthmatic agent.

REFERENCES:
patent: 3915968 (1975-10-01), Bellasio et al.
patent: 4136182 (1979-01-01), Lewis et al.
patent: 5145850 (1992-09-01), Miyake et al.
patent: 5155108 (1992-10-01), Miyake et al.
patent: 5202324 (1993-04-01), Miyake et al.

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