Carbostyril derivatives and salts thereof and anti-arrhythmic ag

Details Carbostyril derivatives and salts thereof and anti-arrhythmic ag Carbostyril derivatives and salts thereof and anti-arrhythmic ag

1991-03-06

1994-10-25

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142352, 5142325, 544 586, 544521, 544362, 544363, A61K 3154, A01N 4304, C07D40100

Patent

active

053589491

ABSTRACT:
Carbostyril derivatives or salt thereof, including novel compounds, having activities for curing and/or improving arrhythmia.
Some carbostyril derivatives having similar chemical structural formula to those of carbostyril derivatives of the present invention are known in the prior art references, however, above-mentioned pharmacological activities have not been known yet.

REFERENCES:
patent: 4014883 (1977-03-01), Fryer et al.
patent: 4284768 (1981-04-01), Santilli
patent: 4374138 (1983-02-01), Haskell et al.
patent: 4395414 (1981-04-01), Eistetter et al.
patent: 4415572 (1983-11-01), Tominaga et al.
patent: 4710507 (1984-12-01), Campbell et al.
patent: 4728653 (1986-04-01), Campbell et al.
patent: 4735948 (1983-03-01), Wright
patent: 4740513 (1986-11-01), Campbell et al.
patent: 4760064 (1988-07-01), Tominaga et al.
Davis et al., "Synthesis and Antibacterial Activities of Some Chloro Analogs of 3-Amino-3,4-dihydro-1-hydroxycarbostyril" (1975).
Davis et al., "Synthesis of the 3-Methyl and 4-Methyl Derivatives of 3-Amino-3,4-dihydro-1-hydroxycarbostyril and Related Compounds" (1980).
McCord et al., "The Rearrangement of 3-Amino-3,4-dihydro-1-hydroxycarbostyril in Acidic Media (1)" (1972).
Davis et al., "Synthesis and Microbiological Properties of Some Substituted Derivatives of 3-Amino-3,4-dihydrocarbostyril" (1970).
McCord et al., "Rearrangement of Some Chlorosubstituted 3-Amino-3,4-dihydro-1-hydroxycarbostyril in Hydrogen Halide Acids" (1982).
McCord et al., "A Comparative Study of the Rearrangement of Some 6- and 7-Halo-substituted 3-Amino-3,4-dihydro-1-hydroxycarbostyrils in Concentrated Hydrohalic Acids" (1982).
McCord et al., "The Rearrangement of 3-Amino-3,4-dihydro-1-hydroxycarbostyril to 3-Amino-3,4-dihydro-6-hydroxycarbostyril (1)" (1982).
Beilsteins Handbuch, Der Organischen Chemie (1935).
Beilsteins Handbuch, Der Organischen Chemie (1980) (pp. 5715-5716, 5910-5911, 5925-5927, 5933-5934, 6090-6091, 6111, and 6117).
Beilsteins Handbuck, Der Organischen Chemie (1980) (pp. 6442, 6445, 6449-6450, 6463, 6657-6659, 6691-6692).
Forbis et al., "Nybomycin. VII. Preparative Routes to Nybomycin and Deoxynybomycin" (1970).
Chemical Abstracts, vol. 84, No. 25 (Jun. 21, 1976), 84:180077w to Otsuka Pharm. Co.
Chemical Abstracts, vol. 85, No. 21 (Nov. 22, 1976), 84:159912a to Otsuka Pharm. Co.
Chemical Abstracts, vol. 93, No. 5 (Aug. 4, 1980), 93:46437w, 93:46438x to Otsuka Pharm. Co.
Talati et al., "Synthesis of Potential Antimalarials: Primaquine Analogs" (1981).
Kauffmann et al., "Uber das intermediare Auftreten von 3,4-Dehydro-carbostyril and 1-Methyl-3,4-dehydro-carbostyril" (1970).
Bowman et al., "The Synthesis of Some Dialkylamino-2-quinolones" (1965).
Bowman et al., "The Synthesis of Some 3-Aminohydrocarbostyrils" (1965).
Petersen et al., "New Methods for the Preparation of 1,4-Benzodiazepiniones, Carbostyrils and Indolo[2,3-c]quinolones" (1969).
Nishimura et al., "Synthesis of 4-Hydroxy-2(1H)-quinolone Derivatives" (1970).
Eistert et al., "Darstellung and Umsetzongen von Pyridyl-(3)-und Pyridyl-(4)-diazomethan" (1966).
Weichert, "Uber threo- underytro-beta-(Aminophynyl)-serine" (1966).
Tominaga et al., "Studies on Positive Inotropic Agents. I. Synthesis of 3,4-Dihydro-6-[4-(3,4-dimethylbenzoyl)-1-piperazinyl]-2(1H)-quinolone and Related Compounds" (1984).

Affiliated with

Also associated with

Rating

Carbostyril derivatives and salts thereof and anti-arrhythmic ag does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carbostyril derivatives and salts thereof and anti-arrhythmic ag, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbostyril derivatives and salts thereof and anti-arrhythmic ag will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-135592