Process for making 2-oxindole-1-carboxamides and intermediates t

Details Process for making 2-oxindole-1-carboxamides and intermediates t Process for making 2-oxindole-1-carboxamides and intermediates t

1986-07-22

1987-03-24

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548431, 548486, C07D20934, C07D40502

Patent

active

046526587

ABSTRACT:
Preparation of 2-oxindole-1-carboxamides by reaction of 2-oxindoles with chlorosulfonyl isocyanate to produce novel N-chlorosulfonyl-2-oxindole-1-carboxamides which are then hydrolyzed to 2-oxindole-1-carboxamides useful as intermediates for analgesic and antiinflammatory agents.

REFERENCES:
patent: 3923996 (1975-12-01), Hardtmann
Graf, Angew. Chem. Internat. Edit., 7, (1968), pp. 172-182.
Rasmussen et al., Chem. Rev., 76, (1976), pp. 389-408.
Szabo, Aldrichimica Acta, 10, (1977), pp. 23-29.

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