Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-03-04
1987-03-24
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
71 92, 544319, A61K 31505, C07D23902
Patent
active
046525696
ABSTRACT:
Disclosed herein are thiocyanopyrimidine derivatives represented by the following general formula: ##STR1## wherein R means an alkyl group having 1-3 carbon atoms and X denotes a halogen atom, their production process, and agricultural and horticultural fungicides containing same as active ingredients. The compounds of this invention can provide ideal agricultural and horticultural fungicides, since they exhibit outstanding fungicidal activities against plant pathogens led by late blight and downy mildew, their toxicity to animals are low and they are not phytotoxic.
The compounds of this invention can be obtained by reacting pyrimidine derivatives represented by the following general formula: ##STR2## with thiocyanates while using an organic acid as a solvent. Good results can be obtained particularly when formic acid is used as a solvent.
REFERENCES:
Kinugawa et al, Chem. Abst., vol. 60, 8061, 8062.
Razavi, Chem. Abst., 72-3499s.
Journal Pharmaceutical Society of Japan, vol. 83, No. 11, 1963, pp. 1086-1091.
Iida Noboru
Inami Shunichi
Ishikawa Katsutoshi
Ozawa Shuji
Shimotori Hitoshi
Daus Donald G.
Mitsui Toatsu Chemicals Incorporated
Shen C.
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