Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1985-11-25
1987-03-24
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 5, 536 62, A61K 31705
Patent
active
046525530
ABSTRACT:
Described are derivatives of glycolipids with substituted steroids bridged via a medium length hydrocarbon chain to 1-thio-D-mannopyranoses or 1-thio-L-fucopyranoses. These compounds protect an immunocompromised human or animal host against opportunistic infection by virtue of their immunostimulant properties.
REFERENCES:
patent: 4189471 (1980-02-01), Ponpipom et al.
patent: 4228274 (1980-10-01), Ponpipom et al.
patent: 4229441 (1980-10-01), Bugianesi et al.
patent: 4259324 (1981-03-01), Ponpipom et al.
patent: 4301152 (1981-11-01), Ponpipom
Chabala et al., "Chem. Abst.", vol. 90, 1979, p. 23588v.
Merck and Co., Inc. "Chem. Abst.", vol. 94, 1981, p. 180690x.
Ponpipom et al., "Chem. Abst.", vol. 99, 1983, p. 122792z.
Carbohydrate Res. vol. 67, pp. 55-63 1979.
J. Med. Chem., vol. 23, p. 1134 (1980).
Can. J. Chem., vol. 58, pp. 214-220 (1980).
Chem. Pharm. Bull. Jap., vol. 12, pp. 528-532 (1964).
P.N.A.S., vol. 78, pp. 7294-7298 (1981).
J. Med. Chem., vol. 15, No. 12, pp. 1284-1287 (1972).
J. Org. Chem., vol. 43, pp. 2923-2925 (1978).
Computer Literature Search Surgery, vol. 92, No. 2, pp. 138-145 "Pros. for Control of Host Defenses" Infection, vol. 12, No. 3, pp. 230/182 to 234/86 (1984).
Durette Philippe L.
Hagmann William K.
Ponpipom Mitree M.
Brown Johnnie R.
Merck & Co. , Inc.
North Robert J.
Pfeiffer Hesna J.
Speer Raymond M.
LandOfFree
Steroidal glycolipids as host resistance stimulators does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Steroidal glycolipids as host resistance stimulators, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Steroidal glycolipids as host resistance stimulators will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1354027