Process for preparing aryl-substituted aliphatic carboxylic acid

Details Process for preparing aryl-substituted aliphatic carboxylic acid Process for preparing aryl-substituted aliphatic carboxylic acid

1992-12-28

1993-10-19

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562406, 560 9, 560 20, 560 21, 560 55, 560 56, 560100, C07C 6976, C07C 5110

Patent

active

052547205

ABSTRACT:
A new process for preparing aryl substituted aliphatic carboxylic acids or then alkyl esters is provided. A 1-aryl substituted olefin is reacted with carbon monoxide in the presence of water or an alcohol at a temperature between about 25.degree. C. and about 200.degree. C. An excess of several moles of water or alcohol is preferred. An acid such as hydrochloric acid may also be added. As catalyst, a mixture of a palladium compound and a copper compound with at least one acid-stable ligand are present.

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