Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-02-22
1993-10-19
Lee, Mary C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
548113, 548114, 548116, 548117, 548118, C07F 928
Patent
active
052546918
ABSTRACT:
A phosphorylating agent represented by the following general formula [1]: ##STR1## wherein R represents a protective group of the phosphoric acid; and X represents a heterocyclic residue represented by the following general formula [2]: ##STR2## wherein Y represents a single bond or an oxygen or sulfur atom; Z represents a heterocyclic nucleus comprising at least one nitrogen atom as a ring-forming element and may be condensed with another aromatic ring; and W represents one or more substituents other than a hydrogen atom. The phosphorylating agent is stable, can rapidly proceed phosphodiester bond-forming reactions in good selectivity under mild conditions and thus makes it possible to perform a reaction even in a relatively large scale.
REFERENCES:
patent: 4474947 (1984-10-01), Hudson et al.
patent: 4476301 (1984-10-01), Imbach et al.
CA 110:154782h Analogs of . . . biosynthesis. Broxterman, et al. p. 771, 1989.
Chemical Abstracts, vol. 86, No. 9, Feb. 26, 1977, Columbus, Ohio, US; Abstract No. 55668, p. 463.
Fuji Photo Film Co. , Ltd.
Lee Mary C.
McKane Joseph K.
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