Multiply substituted anilines, phenols and pyridines-immunomodul

Details Multiply substituted anilines, phenols and pyridines-immunomodul Multiply substituted anilines, phenols and pyridines-immunomodul

1991-12-31

1993-10-19

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514349, 514563, 514616, 514619, 514622, 546297, 562455, 564155, 564157, 564158, 564169, 564171, A61K 31165, C07C23365

Patent

active

052545920

ABSTRACT:
In accordance with the present invention, certain multiply substituted anilines, phenols and pyridines and pharmaceutically acceptable salts thereof are provided which mimic IL-1 activity by inducing IL-2 synthesis and subsequent IL-2 receptor expression. Specifically, the invention provides compounds of Formula I and acid addition salts thereof: ##STR1##

REFERENCES:
patent: 2756149 (1956-07-01), Saunder et al.
patent: 2772163 (1956-11-01), Tong
patent: 4263039 (1981-04-01), Noguchi et al.
patent: 4471045 (1984-09-01), Bodem et al.

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