Treatment of pulmonary dysfunction with 15-ketoprostaglandin com

Details Treatment of pulmonary dysfunction with 15-ketoprostaglandin com Treatment of pulmonary dysfunction with 15-ketoprostaglandin com

Filed on

1992-06-02

Date issued

1993-10-19

Examiner

Waddell, Frederick E.

Patent Class

Drug, bio-affecting and body treating compositions

SubClass

Designated organic active ingredient containing

SubSubClass

Radical -xh acid, or anhydride, acid halide or salt thereof...

Other Related Categories

A61K 3119, A61K 31557

Type

Patent

Status

active

Patent number

052545881

Description

ABSTRACT:
A method for treatment of a pulmonary dysfunction which comprises administering, to a subject in need of such treatment, a 15-ketoprostaglandin compound in an amount effective in treatment of the pulmonary dysfunction.

REFERENCES:
patent: 4639461 (1987-01-01), Nakane
patent: 4680288 (1987-07-01), Irmscher et al.
Medicinal Chemistry, 3rd ed. Alfred Burger Wiley-Interscience, N.Y. (1970) pp. 71-72, 74-75.
STN File Server & File Chemical Abstracts, col. 102, No .1, abstract No. 1100u, Columbius Ohio, US; P. Conzen et al.: "Hypoxic pulmonary vasoconstriction and endogenous prostaglandin (PG) and thromoboxane (TX) release in anesthetized pigs";, & Biomed. Biochim. Acta, 43 (8-9), 265-268, 1984.
Acta Physiologica Scandinavica, vol. 66, 1966, pp. 509-510; E. Anggard: "The biological activities of three metabolites of prostangladin E1".
STN File Server & File Chemical Abstracts, vol. 88, No. 25, abstract No. 183485w, Columbus, Ohio, US: P. Yong Lo: "Effects of pulmonary metabolites of prostaglandins E2 and F2. alpha. on guinea-pig respiratory tract" & J. Pharm. Pharmacol., 29(12), 752-755, 1977.

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