Stereoselective synthesis of a chiral cis 3-beta hydrogen (3R) 4

Details Stereoselective synthesis of a chiral cis 3-beta hydrogen (3R) 4 Stereoselective synthesis of a chiral cis 3-beta hydrogen (3R) 4

1992-01-09

1992-09-08

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540357, C07B 3710, C07D20508, C07F 718

Patent

active

051459574

ABSTRACT:
A process is described for the stereocontrolled synthesis of (3R,4R)-3-[(1R)-1-hydroxyethyl]-4-benzoyloxyazetidin-2-ones and their derivatives by cycloaddition involving an imine and a ketone, generated from 3(S)-hydroxybutyrate which are useful intermediates in the synthesis of carbapenem antibiotics.

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Translation of DE 3620467.

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