Disubstituted aryl compounds exhibiting selective leukotriene B4

Details Disubstituted aryl compounds exhibiting selective leukotriene B4 Disubstituted aryl compounds exhibiting selective leukotriene B4

1990-09-24

1993-05-11

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

562455, 548252, C07D25704, A61K 3141, A61K 3116, C07E22307

Patent

active

052102084

ABSTRACT:
Monocyclic and bicyclic aryl ring compounds having selective LTB.sub.4 properties and comprising two ring substituents, the first substituent comprising a lipophilic group and a terminal carboxylic acid or derivative group, and the second substituent comprising an amido group, therapeutic compositions and methods of treatment of disorders which result from LTB.sub.4 activity using the mono- and bicyclic aryl compounds are disclosed.

REFERENCES:
patent: 4727180 (1988-02-01), Aldrich et al.
patent: 4820722 (1989-04-01), Carr et al.
patent: 5140046 (1992-08-01), Mase et al.

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