Biphenyl oxadiazoles and thiadiazoles as angiothesin II antagoni

Details Biphenyl oxadiazoles and thiadiazoles as angiothesin II antagoni Biphenyl oxadiazoles and thiadiazoles as angiothesin II antagoni

1992-06-16

1993-05-11

Cintins, Marianne M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548132, 548136, 546118, 546153, 546277, 544284, 544319, C07D27110, C07D28512

Patent

active

052102041

ABSTRACT:
Heterocyclic methyl derivatives of biphenyl oxadiazoles and thiadiazoles are described, as well as methods for the preparation of said derivatives and pharmaceutical compositions of the same, which are useful as antagonists of the angiotensin II enzyme and thus useful in treating hypertension, hyperaldosteronism, congestive heart failure, and glaucoma.

REFERENCES:
patent: 4618617 (1986-10-01), Yamamoto
patent: 5086053 (1992-02-01), Brodin et al.
patent: 5100897 (1992-03-01), Allen et al.
patent: 5102897 (1992-04-01), Boschelli et al.

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