Human monoclonal antibody, and its production and use

Details Human monoclonal antibody, and its production and use Human monoclonal antibody, and its production and use

1990-04-24

1993-03-23

Doll, John J.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 7021, 5303884, 53038815, 5303882, C12N 512, C12P 2108, C07K 1528

Patent

active

051963370

ABSTRACT:
A human monoclonal antibody, which has prophylactic and therapeutic effect to infectious diseases caused by Pseudomonas aeruginosa of serotypes A and H classified under the Japanese Committee's Classification, and the epitope of which is located at the common structure in the O-antigen of Pseudomonas aeruginosa of serotypes A and H. A hybridoma producing said human monoclonal antibody, and processes for preparing said hybridoma and antibody are also provided.

REFERENCES:
patent: 4918163 (1990-04-01), Young et al.
Kozbor, D. et al., Eur. J. Immunol., 14:23-27 1984.
Teng, N. N. H. et al., Proc. Natl. Acad. Sci., 82:1790-1794, Mar. 1985.
Zeerink et al., Infection and Immunity, vol. 56, No. 8, pp. 1873-1879, 1988.

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