Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1990-11-05
1993-05-11
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
4241951, 424 944, 514567, A61K 3700
Patent
active
052100766
ABSTRACT:
The invention is directed to the treatment of degenerative diseases of tissues which have lost melanin and which share a common embryological basis as tissues of the nervous system by the administration of an active substance which causes an increased concentration of melanin in the tissue. Such active substances include melanin, melanin variants, melanin analogs, melanin derivatives, tyrosinase, tyrosinase gene, melanin-concentrating hormone and combinations thereof. Examples. of such diseases include Parkinson's disease, Alzheimer's disease, retinitis pigmentosa, schizophrenia and dementia. The invention is also useful in assisting in the repair of neurons in a mammal having neuron damage by administering an effective amount of an active substance which causes an increased concentration of melanin in the neuron to aid in nerve repair. The invention is further useful in protecting a mammal from a toxin-induced disease or from the adverse effects of a toxin by administering an effective amount of the active substance described above.
REFERENCES:
Cotzias et al-New Eng. J. of Medicine, vol. 276, No. 7, pp. 374-379 (1967).
Mann et al-Mechanisms of Ageing & Develop, vol. 21, 193-203 (1983).
Atscholte et al-Clinical Pharm. & Therapeutics vol. 19, No. 2, 124-34 (1976).
Berliner David L.
Erwin Robert L.
McGee David R.
LandOfFree
Methods of treating Parkinson's disease using melanin does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of treating Parkinson's disease using melanin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of treating Parkinson's disease using melanin will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1350036