Interleukin 6 antagonist peptides

Details Interleukin 6 antagonist peptides Interleukin 6 antagonist peptides

1990-02-16

1993-05-11

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 13, 514 15, 530326, 530327, 530328, A61K 3702, C07K 106, C07K 108

Patent

active

052100758

ABSTRACT:
Peptides and derivatives useful as antagonists to interleukin 6, and uses for the same, are disclosed.

REFERENCES:
Hirano, et al, Nature, vol. 324, pp. 73-76, 1986.
Palaszynski, "Synthetic C Terminal Peptide of IL-1 Functions as a Binding Domain As Well As An Antago Hist For The IL-1 Receptor", Biochemical and Biophysical Research Communication, vol. 147, No. 1, pp. 204-211, 1987.
Auron, et al, "Nucleotide Sequence of Human Monocyte Interleukin 1 Precursor cDNA", Proc. Natl. Acad. Sci. USA, vol. 81 pp. 7907-7911, 1984.

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