Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1993-06-09
1994-10-25
Hill, Jr., Robert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 691, 4351723, 536 234, C12N 1512, C12N 1562
Patent
active
053588576
ABSTRACT:
Fusion proteins are obtained in high yields if a mixed oligonucleotide is constructed which codes for the ballast constituent of the fusion protein. The oligonucleotide mixture is introduced in a vector in such a manner that it is functionally linked to a regulatory region and to the structural gene for the desired protein. Appropriate host cells are transformed with the plasmid population obtained in this manner and the clones producing a high yield of coded fusion protein are selected.
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Habermann Paul
Seed Brian
Stengelin Siegfried
Uhlmann Eugen
Hill Jr. Robert J.
Hoechst Aktiengesellschaft
The General Hospital Corp.
Ulm John D.
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