Phenylpiperazine derivatives of hetarylphenols and hetarylanilin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544366, 544367, 544370, 544371, C07D41312, C07D40312, C07D41712, A61K 31495

Patent

active

046199292

ABSTRACT:
Novel phenylpiperazinylpropane and -butane derivatives of hetarylphenols and hetarylanilines of the formula ##STR1## where R.sup.1 is hydrogen or alkyl of 1 to 4 carbon atoms, R.sup.2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R.sup.2, X is oxygen or an NH group, and the heterocyclic structure Het. is 1,3,4-oxadiazolyl, triazolyl, imidazolyl or pyrazolyl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly sedative, neuroleptic and hypotensive properties.

REFERENCES:
patent: 3937708 (1976-02-01), Mentrup et al.
patent: 3941789 (1976-03-01), Renth et al.
patent: 4353904 (1982-10-01), Thieme et al.
patent: 4428950 (1984-01-01), Franke et al.

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