GNRH antagonists IIIB

Details GNRH antagonists IIIB GNRH antagonists IIIB

1984-02-23

1986-10-28

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514800, 530313, A61K 3743, C07K 720

Patent

active

046199144

ABSTRACT:
Peptides which inhibit the secretion of gonadotropins by the pituitary gland and inhibit the release of steroids by the gonads. Administration of an effective amount prevents ovulation of female mammalian eggs and/or the release of steroids by the gonads. The peptides have the structure:

REFERENCES:
patent: 4215038 (1980-07-01), Rivier et al.
patent: 4234571 (1980-11-01), Nestor et al.
patent: 4253997 (1981-03-01), Sarantakis
patent: 4292313 (1981-09-01), Vale, Jr. et al.
patent: 4307083 (1981-12-01), Rivier et al.
patent: 4444759 (1984-04-01), Rivier et al.
Coy et al., Endocrinology, vol. 110, No. 4, 1982, pp. 1445-1447.

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